Overview

My general research interest is in understanding what defines evolutionary trajectories. Within in this interest, I tend to focus on studying the evolution of organismal complexity, which I explore through a variety of subjects, including the evolution of endosymbioses, the evolution of multicellularity, the evolution of outcrossing, and the evolution of developmental/life cycle complexity. I also have an interest in applying the study of evolutionary trajectories towards solving practical problems, which has led me to work as a contractor through the St. George Tanaq Corporation supporting the Centers for Disease Control and Prevention (CDC) efforts to understand viral evolution.

My work primairly involves developing mathematical and computational models for explaining biological phenomena, as well as leveraging available data for applying said models and emperically evaluating general theory. I also enjoy developing more general mathematical and statistical frameworks for drawing inferences from large data sets. In addition to my scientific research, I also focus on studying approaches and developing resources for improving education in evolutinary biology and quantitative biology.

Below is a list of my publications. However, this list was last updated on 05/25/2026, which might not reflect recent additions. A full list of my work can be found on my Google scholar: https://scholar.google.com/citations?user=MGLUGcwAAAAJ&hl=en

* indicates student mentee

2026

DuBose, J.G., Morran, L.T. (2026) Towards a standard model for teaching the process of biological evolution. EcoEvoRxiv. https://doi.org/10.32942/X2G09C

DuBose, J.G. (2026) The roles of density dependence, developmental asynchrony, and niche traversal costs in shaping the evolution of ontogenetic complexity. EcoEvoRxiv. https://doi.org/10.32942/X2NQ3W

DuBose, J.G., Fiedorek, P., Hoogshagen, M., Clark, D., Nolan, A., Gerner, H., Nguyen, P., Gibbs, K., Haselkorn, T.S. (2026) Ecological and evolutionary dynamics of chlamydiaeendosymbionts in social amoeba host communities. EcoEvoRxiv. https://doi.org/10.32942/X2B68T

DuBose, J.G. (2026) FGMLab: An open-source software for teaching biological evolution through Fisher’s geometric model. EvoEvoRxiv. https://doi.org/10.32942/X2TT1Q

Wang, C.Q.*, DuBose, J.G. (2026) Pleiotropy and the evolutionary stability of plastic phenotypes: a geometric framework. G3: Genes | Genomes | Genetics. 16(1): jkaf262. https://doi.org/10.1093/g3journal/jkaf262

DuBose, J.G. (2026) Inferring the dynamics of selective constraints across complex ontogenies. Royal Society Open Science. 13(3): 251846. https://doi.org/10.1098/rsos.251846

Hoogshagen, M., Arega, E.*, DuBose, J.G., Villa, S.M., de Roode, J.C. (2026) The contributions of host diet and genetic background to shaping parasite infection outcomes in monarch butterflies across natural populations. Ecological Entomology (in press). https://doi.org/10.1111/een.70091

2025

DuBose, J.G. (2025) The effects of host phylogenetic coverage and congruence metric on Monte Carlo-based null models of phylosymbiosis. Peer Community Journal. 5: e139. https://doi.org/10.24072/pcjournal.667

DuBose, J.G., Uhm, T., Bowen, J., Fiedorek, P., Hoogshagen, M., Haselkorn, T.S., DiSalvo, S. (2025) The roles of dispersal limitation and pre-adaptation in shaping Paraburkholderia endosymbiont frequencies in social amoeba communities. Applied and Environmental Microbiology (in press). https://doi.org/10.1128/aem.01615-25

Catano, C.P., DuBose, J.G., Fuller-Hall, L., Chavez, J., de Roode, J.C. (2025) Experimental immigration mediates ecological selection and stochasticity in monarch microbiome assembly. Ecology Letters. 28(11): e70252. https://doi.org/10.1111/ele.70252

DuBose, J.G., Morran, L.T. (2025) Reduced signatures of gene organization and duplication in shaping stage-specific patterns of expression across the C. elegans life cycle. Journal of Evolutionary Biology. 38(8): 1143–1151. https://doi.org/10.1093/jeb/voaf061

DuBose, J.G., de Roode, J.C. (2025) Extensive transcriptional differentiation and specialization of a parasite across its host's metamorphosis. International Journal for Parasitology. 55(6): 273-279. https://doi.org/10.1016/j.ijpara.2025.01.006

DuBose, J.G., Crook, T.B.*, Matzkin, L.M., Haselkorn, T.S. (2025) The relative importance of host phylogeny and dietary convergence in shaping the bacterial communities hosted by several Sonoran Desert Drosophila species. Journal of Evolutionary Biology. 38(2): 180-189. https://doi.org/10.1093/jeb/voae143

Junker, A.D., Chen, J.Z., DuBose, J.G., Gerardo, N.M. (2025) Dynamic reciprocal morphological changes in insect hosts and bacterial symbionts. Journal of Experimental Biology. 228(14): jeb249474. https://doi.org/10.1242/jeb.249474

DuBose, J.G., Hoogshagen, M., de Roode, J.C. (2025) The role of a non-native host plant in altering the seasonal dynamics of Danaus plexippus development. Journal of Insect Science. 25(3): ieaf061. https://doi.org/10.1093/jisesa/ieaf061

2024

DuBose, J.G., de Roode, J.C. (2024) The link between gene duplication and divergent patterns of gene expression across a complex life cycle. Evolution Letters. 8(5): 726-734. https://doi.org/10.1093/evlett/qrae028

2023

Pentz, J.T., MacGillivray, K., DuBose, J.G., Conlin, P.L., Reinhardt, E., Libby, E., Ratcliff, W.C. (2023) Evolutionary consequences of nascent multicellular life cycles. eLife. 12:e84336. https://doi.org/10.7554/eLife.84336

2022

DuBose, J.G., Robeson, M.S., Hoogshagen, M., Olsen, H., Haselkorn, T.S. (2022) Complexities of Inferring Symbiont Function: Paraburkholderia Symbiont Dynamics in Social Amoeba Populations and Their Impacts on the Amoeba Microbiota. Applied and Environmental Microbiology. 88(18): e01285-22. https://doi.org/10.1128/aem.01285-22